The fight against cancer has lasted for several centuries, however, the most common cause of death before age 70 is still cancer. With the discovery of immune checkpoint, the immunotherapy has entered a new era. We are trying to understand more on PD-1/PD-L1 pathway. Furthermore, we are trying to understand how tumor autoinflammation affect tumor progress and how tumor inflammation affect PD-1/PD-L1 pathway. Join and help us!